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hema.to is an easy-to-use software for clinical decision support for blood cancer from cytometry data using AI. hema.to makes the diagnostic workflow both faster and better, helping both diagnosticians as well as patients. hema.to is a CE-IVD, FDA registered and already in routine use by leading hematology laboratories. Founded in 2021, hema.to’s mission is to make clinical analysis of cytometry data completely objective, to enable doctors to personalize treatment to their patient’s unique immune system.

Since its operational start in 2017, HepaRegeniX has successfully discovered and developed several drug candidates for the treatment of acute and chronic liver diseases based on a novel proprietary molecular target Mitogen-Activated Protein (MAP) Kinase Kinase 4 (MKK4). A first compound has recently started clinical development.
MKK4 is a key regulator of liver regeneration and suppression of MKK4 unlocks the regenerative capacity of hepatocytes even in severely diseased livers. This new and unique therapeutic concept for the treatment of liver diseases was discovered by Prof. Lars Zender and his research group at the University Hospital Tubingen, Germany. Investors in HepaRegeniX include the Boehringer Ingelheim Venture Fund (BIVF), Novo Holdings A/S, Coparion, High-Tech Gruenderfonds and Ascenion GmbH.

HighLine Technology GmbH develops and commercializes high-precision printing technology for the semiconductor industry. The current focus is the introduction of the parallel dispensing technology for the metallization of solar cells. The dispensing print heads enable parallel and homogeneous printing of high aspect ratio contact linesat finger widths below 30 µm. HighLine’s Dispensing Print Heads thereby enable the reduction of material costs at increased production throughputs for the application of print media. In addition, HighLine develops automation solutions for the integration of print heads in existing production platforms and thus cooperates with established automation manufacturers. The core competences of the company are component and process development for dispensing technologies.

HiperScan GmbH was founded in 2006 as a spin-off of the Dresdner Fraunhofer Institute for Photonic Microsystems (IPMS). The innovative scanning grating technology developed at the IPMS forms the basis for the near-infrared (NIR) spectrometer developed by HiperScan. The analytical systems make it possible to significantly reduce investment costs to make NIR-analytics affordable even to small companies. Today, the company HiperScan stands for high-quality technologies to quickly analyse nutrition facts of processed meat and fish and to reliably qualify pharmaceutical raw materials. So, the product Apo-Ident has been tailored for the safe and easy identification of compounding substances in pharmacies.

Hofmann & Stirner Zuführsysteme GmbH was founded in 2016 by Daniel Hofmann and Florian Stirner. The company develops powerful and flexible feeding systems using digital twins and artificial intelligence. Hofmann & Stirner work closely together with well-known companies in machine and plant construction.
More: www.designforfeeding.com

Hornetsecurity is premium provider of cloud-based security services. Hornetsecurity products protect companies’ IT infrastructure and data.

HQ plus – the new generation of competitive intelligence for hotels.

HQS Quantum Simulations predicts material properties using quantum computers. The company accelerates development cycles in the chemistry and pharma industries. Quantum computers can perform calculations impossible even for the most powerful supercomputers. Current quantum computers suffer from intrinsic errors that limit their performance. The HQS Team developes algorithms for quantum computers that can deal with these errors and enable our customers to profit from the performance advantage of quantum computers earlier than their competitors. Furthermore, HQS offers individual simulation solutions for conventional computers with an integration of high-end simulation methods and the possibility to utilize the upcoming quantum computers.

Humedics markets a system for bedside and instantaneous measurement of liver function. Patented device, consumables and a diagnostic drug allow an optimal market offering.

i3 Membrane is a companion for filtration solutions and separation technologies in life science. With and for the customers, high-quality products in the fields of medical, lab / pharma and biotech are developed. By combining ion and membrane technology and with the help of plasma immersion ion implantation, the first digitally controllable membrane was developed for the i3 as early as 2013 and traditional separation technology was revolutionized.

The membranes equipped with functionalized surfaces enable more efficient and sustainable separation processes and reduce fouling. The digitally switchable adsorption and desorption of various media with simultaneous filtration opens up new possibilities for using membranes in all areas of life sciences. Coated polymer membranes are used for both individual and standardized solutions in healthcare, laboratory technology and pharmaceuticals as well as in research. The range of applications extends from Analytics through Infection prevention to Biotechnology.

Today i3 Membrane is one of the most innovative separation technology companies. Production takes place at the headquarters in Radeberg near Dresden. The young company is characterized by its branches in Germany and Austria and an international sales network.

iAtros is a digital heart clinic and a fully integrated platform, providing better medical care for patients with cardiovascular problems around the clock. Among other services, iATROS offers smart sensor diagnosis, a vital parameter data base, therapy- and medication regimes as well as teledoctor services.
Cardiologists Prof. Dr. med. Alexander Leber and Dr. med Georges von Degenfeld and eHealth entrepreneur Patrick Palacin founded iATROS in 2019. Former Sky executive and communications expert Prof Wolfram Winter and former AOK Berlin finance director Jens Schäfer are the co-founders.

Lighting as a Service: Intelligent lighting with M2M (Machine to Machine) services in outdoor sector with focus on Information, Communication, Energy efficiency (ICE).

Exit since November 2016.

ICO-LUX was founded in 2018 as a spin-off of the Friedrich-Schiller-University Jena and the TU Ilmenau and is specialized in software for automated document forensics. With ICO.Fraud for private health insurance companies, the start-up is the only provider of a software solution for fully automatic detection of forged documents to date. Customers are currently mainly private health insurance companies. ICO-LUX has 7 employees at its Jena site, including mathematicians, physicists and computer scientists with doctorates.

Iconiq Holding is a global crypto asset management firm headquartered in Frankfurt, Germany with offices in London and New York. Iconiq Holding launched Iconiq Lab, the world’s first decentralized venture capital group and token sale accelerator program, in early 2017 and is issuing a series of crypto asset index funds under the Iconiq Funds brand. Iconiq Holding is the developer of the crypto asset management platform, AMaaS, as well as an authorized Sponsor Firm of the Gibraltar Blockchain Exchange (GBX) and the issuer of the ICNQ token.

The immersight® 3D-Showroom is a cloud-based platform for virtual product presentations in stationary, mobile of web applications. Manufactureres can provide all their goods to retailers, who can now present an unlimited product variety through Virtal Reality techology to their customers.

Immunic Therapeutics is a clinical-stage biotech company with a pipeline of selective oral immunology therapies aimed at treating chronic inflammatory and autoimmune diseases. Immunic, Inc. is headquartered in New York. Its subsidiary, Immunic AG, is based in Graefelfing near Munich, Germany, where the company’s research and development activities are conducted. Additional subsidiaries are located in Halle/Saale, Germany, and Melbourne, Australia.

Immunic is developing three small molecule products: lead development program, IMU-838, is a selective immune modulator that inhibits the intracellular metabolism of activated immune cells by blocking the enzyme DHODH; IMU-935 is an inverse agonist of RORγt; and IMU-856 targets the restoration of the intestinal barrier function. IMU-838 is in phase 2 clinical development for COVID-19, relapsing-remitting multiple sclerosis, ulcerative colitis and, in collaboration with the Mayo Clinic, primary sclerosing cholangitis.

IOP GmbH will initiate a paradigm chance in glaucoma therapy by its products for telemetric, 24 hour monitoring of intraocular pressure, allowing personalized patient management.

Implisense offers a solution for lead generation as well as cross- and upselling for B2B marketing and sales. Their self-developed company index, which is kept up-to-date on a day-to-day basis and stores information about several million companies in Germany is the foundation of their solution. Users can obtain access to this index via a Web-based interface and perform their own customer and market analysis. The solution can compute a target profile based on examples of a user’s existing customers. With the help of this profile the solution can recommend new potential customers as well as cross- and upselling opportunities immediately.

Error-prone manual labor and frustrating communication loops – to date, large companies need multiple days to publish a new app version. With incapptic Connect it's a matter of seconds: Our software simplifies the data exchange with external developers. incapptic Connect signs automatically with your enterprise's private keys. incapptic Connect is compatible with popular app distribution systems such as MobileIron, Apple App Store and Google Play. It enables large enterprises to move as fast as startups. incapptic Connect saves you money, time, and sanity.

InCephalo develops exclusively local treatments for neurological diseases, with a focus on cancers in the brain (primary brain cancers as well as secondary brain cancers). The proprietary Compartment Lock technology, also called C-Lock, retains biologics, that are applied locally behind the blood brain barrier, in the central nervous system (CNS) and once they leave the CNS, degrades them rapidly in the systemic compartment. Thereby it significantly improves local CNS therapy, a challenging task with regards to achieving high local concentration (for efficacy) and low systemic footprint (to reduce potential side effects). Especially the peripheral side effects still limit various promising candidates for the treatment of brain cancer or other neurological diseases.

InCirT is a deep-tech start-up which provides semiconductor IP solutions for high-speed wireless networks. The core product of the company is a digital-analog / analog-digital converter (a so called “transceiver”), which in its final version will enable data transmission of up to 1 Tbps. The company was started at RWTH Aachen. It was founded in the beginning of 2022 while participating in the EXIST technology transfer program. The InCirT founder team consists of Dr. Oner Hanay, Dr. Erkan Bayram, Dr. Mohamed Saeed Elsayed, Sebastian Waters und Univ.-Prof. Dr. sc. techn. Renato Negra.

inContAlert was founded in September 2022 within the ecosystem of the University of Bayreuth. The MedTech startup's sensor system empowers patients with neurogenic bladder dysfunction to manage their bladder on a needs-based basis.

Founded by Thilo Hardt and Tony Twyman, two veterans of the startup ecosystem of Berlin. Hardt co-founded Mister Spex, Europe’s leading online optician in 2007, and founded eWings.com, a business travel management software company in 2013, now part of American Express GBT. Both are software developers at heart and eager to make great games that a new generation of kids will soon recall as part of their youth.

Renewable electricity and yet unused, undervalued gases (e.g. CO2) can be converted into sustainable products such as climate neutral gasoline, clean Diesel and e-kerosene, high-quality waxes, green methanol or renewable synthetic natural gas (altogether: e-products). INERATEC (IC) sells compact plants for these conversions or invests into e-product production sites.
IC´s technology solves several challenges of the energy transition: management of a fluctuating supply of renewable energy, large and long-term energy storage as well as sustainable mobility and climate neutrality. Synthetic fuels will especially be needed for heavy-duty and maritime transportation as well as aviation. E-products are a viable option for the defossilization of many industries currently depending on fossil resources.

Innerspace develops novel, psychologically based training solutions for highly critical applications in the life science industry. Cleanroom operators are comprehensively prepared for the key moments of their work using the DeepTraining approach, implemented in virtual reality. With regular practice in virtual space, they can safely deepen their behaviour patterns and their understanding of production in critical areas of activity. Since company foundation Innerspace has positioned itself clearly as the innovator combining content and VR-technology in the Edu-Tech-Market. Innerspace already sells its products to numerous leading international pharma companies.

Inovedis is developing a new surgical technique for rotator cuff ruptures based on a PEEK implant. This injury is by so far the most typical shoulder injury. The patented SINEFIX implant system allows refixation of the tendon with a simplified surgical technique and is optimized for minimally invasive surgery. The technique is easy and quick to learn for the surgeon, minimizing complications due to surgical mistakes. The novel surgical principle suggests significant time and cost reductions as well as improved outcomes. Inovedis was founded in 2016. The company started operations in 2019.

instagrid is specialised in mobile off-grid batteries, driving the energy system transition for off-grid electricity, which today is still dominated by combustion engines. With its patented technology, instagrid offers the provision of clean mobile power without compromises enabling the off-grid economy of tomorrow to power their work in a sustainable way. Already shipping to the entire EU, instagrids market-leading product, instagrid ONE, provides professionals in sectors such as construction, events or public safety with reliable and efficient access to electricity to replace highly polluting generators.

Intelligent fluids GmbH is designing innovative high performance cleaning fluids for industrial application that are unique in the world. These intelligent fluids® are based on a groundbreaking, patented technology that combines gentle ingredients to create highly dynamic phase fluids tailored to specific needs. The highly effective fluids achieve their outstanding performance due to physical effects, no chemical dissolving or etching takes place. The fluids therefore combine high performance and sustainability.

INVENTORUM connects local trading and the online world. Founded in 2013, INVENTORUM offers a POS solution that enables retailers to optimize all responsibilities and activities. The modern software combines a cash point, inventory management, accounting and e-commerce in just one app. Additional hardware, such as receipt printers and barcode scanners, is easy to connect. With so many functions that more than meet the requirements of cash register software in 2018, INVENTORUM is truly the digital cockpit of the future for retail.

Founded by Johann Olsen, Nabil Imran and Felix Kruse in Flensburg, the IT company IO-Dynamics supports its customers in making the operation of electric vehicles in companies simple and cost-effective. It sees itself as a manufacturer-independent provider to meet the requirements of different charging stations and electric vehicles today and in the future. Its product IO-ELON creates a link between the energy and mobility sectors, as electric vehicles are charged according to demand and in coordination with energy generation. For companies with electric vehicle fleets in particular, this means greater transparency in the operation of vehicles and energy management that reduces costs and administrative work and responds to the individual needs of fleet operators.