Portfolio Finder

iAtros is a digital heart clinic and a fully integrated platform, providing better medical care for patients with cardiovascular problems around the clock. Among other services, iATROS offers smart sensor diagnosis, a vital parameter data base, therapy- and medication regimes as well as teledoctor services.
Cardiologists Prof. Dr. med. Alexander Leber and Dr. med Georges von Degenfeld and eHealth entrepreneur Patrick Palacin founded iATROS in 2019. Former Sky executive and communications expert Prof Wolfram Winter and former AOK Berlin finance director Jens Schäfer are the co-founders.

Immunic Therapeutics is a clinical-stage biotech company with a pipeline of selective oral immunology therapies aimed at treating chronic inflammatory and autoimmune diseases. Immunic, Inc. is headquartered in New York. Its subsidiary, Immunic AG, is based in Graefelfing near Munich, Germany, where the company’s research and development activities are conducted. Additional subsidiaries are located in Halle/Saale, Germany, and Melbourne, Australia.

Immunic is developing three small molecule products: lead development program, IMU-838, is a selective immune modulator that inhibits the intracellular metabolism of activated immune cells by blocking the enzyme DHODH; IMU-935 is an inverse agonist of RORγt; and IMU-856 targets the restoration of the intestinal barrier function. IMU-838 is in phase 2 clinical development for COVID-19, relapsing-remitting multiple sclerosis, ulcerative colitis and, in collaboration with the Mayo Clinic, primary sclerosing cholangitis.

IOP GmbH will initiate a paradigm chance in glaucoma therapy by its products for telemetric, 24 hour monitoring of intraocular pressure, allowing personalized patient management.

InCephalo develops exclusively local treatments for neurological diseases, with a focus on cancers in the brain (primary brain cancers as well as secondary brain cancers). The proprietary Compartment Lock technology, also called C-Lock, retains biologics, that are applied locally behind the blood brain barrier, in the central nervous system (CNS) and once they leave the CNS, degrades them rapidly in the systemic compartment. Thereby it significantly improves local CNS therapy, a challenging task with regards to achieving high local concentration (for efficacy) and low systemic footprint (to reduce potential side effects). Especially the peripheral side effects still limit various promising candidates for the treatment of brain cancer or other neurological diseases.

inContAlert was founded in September 2022 within the ecosystem of the University of Bayreuth. The MedTech startup's sensor system empowers patients with neurogenic bladder dysfunction to manage their bladder on a needs-based basis.

Renewable electricity and yet unused, undervalued gases (e.g. CO2) can be converted into sustainable products such as climate neutral gasoline, clean Diesel and e-kerosene, high-quality waxes, green methanol or renewable synthetic natural gas (altogether: e-products). INERATEC (IC) sells compact plants for these conversions or invests into e-product production sites.
IC´s technology solves several challenges of the energy transition: management of a fluctuating supply of renewable energy, large and long-term energy storage as well as sustainable mobility and climate neutrality. Synthetic fuels will especially be needed for heavy-duty and maritime transportation as well as aviation. E-products are a viable option for the defossilization of many industries currently depending on fossil resources.

Innerspace develops novel, psychologically based training solutions for highly critical applications in the life science industry. Cleanroom operators are comprehensively prepared for the key moments of their work using the DeepTraining approach, implemented in virtual reality. With regular practice in virtual space, they can safely deepen their behaviour patterns and their understanding of production in critical areas of activity. Since company foundation Innerspace has positioned itself clearly as the innovator combining content and VR-technology in the Edu-Tech-Market. Innerspace already sells its products to numerous leading international pharma companies.

Inovedis is developing a new surgical technique for rotator cuff ruptures based on a PEEK implant. This injury is by so far the most typical shoulder injury. The patented SINEFIX implant system allows refixation of the tendon with a simplified surgical technique and is optimized for minimally invasive surgery. The technique is easy and quick to learn for the surgeon, minimizing complications due to surgical mistakes. The novel surgical principle suggests significant time and cost reductions as well as improved outcomes. Inovedis was founded in 2016. The company started operations in 2019.

Intelligent fluids GmbH is designing innovative high performance cleaning fluids for industrial application that are unique in the world. These intelligent fluids® are based on a groundbreaking, patented technology that combines gentle ingredients to create highly dynamic phase fluids tailored to specific needs. The highly effective fluids achieve their outstanding performance due to physical effects, no chemical dissolving or etching takes place. The fluids therefore combine high performance and sustainability.

KINAXO supports pharmaceutical companies in the development of targeted drugs and predictive biomarkers for personalized healthcare.

Exit since Feb. 2011. Purchaser: Evotec AG

The founders of Kumovis GmbH have set themselves the goal of enabling the additive production of plastic implants and are developing innovative 3D printers specifically for medical products. Kumovis focuses on the processing of high-performance polymers, which are already established in medical technology. With the Kumovis system these plastics can be processed individually, decentrally and with a high degree of design freedom. Through the integration of a unique air circuit including filter units, the technology enables a clean room environment within the build chamber. The contamination of the component with foreign particles can be avoided. As a result, the Kumovis printer can produce products such as implants cost-effectively and at the same time patient-individualized.

LignoPure GmbH is a spin-off of the TU Hamburg that enables the valorization of Lignin, a byproduct of ethanol biorefineries and the pulp and paper industry, via a proprietary technology. The startup is pioneering in the use of lignin in care products and biobased high-performance materials. As key technology partner, LignoPure supports their customers in launching their own innovative and sustainable products by not only providing the tailored raw material but offering development services in the areas of material and life sciences.

Lindis Blood Care is developing a medical device to be used in oncology for the operation of tumours in order to open up the possibility of self-blood administration of blood collected during the operation. The product consists of a combination of an antibody and filter and serves to remove cancer cells from the blood.

lino Biotech AG was incorporated as a ETH Zurich spin-out in Zürich, Switzerland, in March 2020, and is venture backed by Roche Venture Fund, High-Tech Gründerfonds and several lifescience family offices. lino offers industry partners and researchers a unique way to study molecular interactions in living cells and crude biosystems.

Lipocalyx develops transfection reagents. Our Viromers® are polymers emulating a viral mechanism for cell entry. The company provides reagents and currently establishes services for pharmaceutical applications.

LOEWI GmbH is a scientific spin-off of the TU München with the mission to make personalized health and nutrition available to everyone by combining science and technology. LOEWI's patented personalization concept analyzes health relevant data of customers and patients, makes the analysis available via LOEWI's Health Profile (Medical Software Class I), and creates personalized nutrient recommendations and therapies using a sophisticated recommendation algorithm, which are 100% tailored to the personal needs of each customer and patient.

Lymphatica Medtech develops medical devices for lymphatic disease treatment. The first product, LymphoDRAIN, is the worldwide first active lymphatic bypass for the treatment of chronic lymphedema, a disabling disease affecting millions of people worldwide.
Lymphatica developed its implantable drainage technology as a results of years of research at the Lausanne Federal Institute of Technology (EPFL) and of the Lausanne University Hospital (CHUV).

m2p-labs supplies microbioreactor systems focusing on micro fermentations and automated solutions for screening and bioprocess development. The product portfolio comprises high-throughput BioLector® micro fermentation systems, microtiter FlowerPlate® plates, and automated cultivation RoboLector® platforms, an integration of the BioLector® tool into a liquid handling system.
Proprietary online monitoring technology increases the number and the information content of microbial experiments, either aerobic, microaerophilic, or strictly anaerobic. Experiments can be conducted with excellent efficiency and high quality at low costs in microscale.

Mbiomics is a Munich based microbiome startup company which was founded by Dr. Laura Figulla (CEO), Dr. Johannes Wöhrstein (CTO), and Dr. Markus Rinecker (CMO) in 2020. With its proprietary microbiome profiling technology at hand, mbiomics is uniquely positioned to understand microbiome modulation and to design effective microbiome therapies.

MDTB stands for drugs, which are based on the immunomodulating drug substance Desacell®.
Desacell® is an advanced drug platform based on MSC (Mesenchymal Stromal Cells) and addresses many inflammatory-associated diseases for which there are currently no satisfactory therapies and which lead to high mortality or poor quality of life. Examples include septic shock, acute GvHD and the lung disease BPD.
The mission of MDTB Cell Manufacturing GmbH is the industrial-pharmaceutical production of MSC-based drugs in Germany as clinically well manageable Advanced Therapy Medical Products (off-the-shelf/ready-to-use) to significantly improve the health of affected patients. The manufacturing costs and the progress made in scaling up should also enable application in large patient groups.
Desacell® is currently being tested internationally in several clinical studies.

mediaire GmbH was founded in 2018 in Berlin by experienced MRT and AI experts in order to support radiologists with innovative software solutions for the automatic diagnosis of MRT images. mediaire's solutions can be fully integrated into the internal IT infrastructure of radiology centers to ensure a smooth workflow and the highest possible protection of sensitive patient data. The first product md.Brain, which can be used for early detection and follow-up of neurodegenerative diseases, is already certified as a medical device and is therefore available for immediate use. Among the co-founders are two medical physicists with expertise in MRI and CI (Dr. Andreas Lemke and Dr. Jörg Döpfert), as well as two experienced scientists and specialists in radiology (Prof. Dr. med. Henrik Michaely and Prof. Dr. med. Michael Fenchel).

miRdetect is a biotechnology company founded in 2016, with the aim to revolutionise cancer diagnostics. The focus is on development, production and distribution of in-vitro diagnostics based on molecular diagnostic methods. The first product, based on the quantification of microRNA, is a blood test for the detection of testicular cancer. The high sensitivity and accuracy of the test improves the diagnosis and therapy of patients significantly and reduces the costs for the health care system. miRdetect has developed a patented platform technology, which allows the exact and reliable quantification of small amounts of genetic material in body fluids. This robust method represents the basis for the development of additional diagnostic tests.

Mosanna is a Swiss Biotech company based in Basel with a commitment to improving patient outcomes and quality of life in high unmet need diseases, applying a precision medicine approach. We carefully select innovative medicines for further development using the best contract research organisations in the specific specialised field. Our first goal is to bring an effective and well tolerated medicinal nasal spray to Metabolic Obstructive Sleep Apnea patients.

multiBIND develops innovative solutions for molecular biology, healthcare and agriculture. bioDECONT® and bioCLEAN represent biocompatible disinfection and decontamination in laboratories, hospitals and agriculture.

MYR develops a novel, peptide-based, first-in-class drug (entry inhibitor) for the treatment of chronic hepatitis B and Delta infections. Clinical phase IIb currently in preparation.

NAVAN, Inc. (NAVAN) is an early-stage private biotechnology company developing a novel, proprietary NanoStraw platform to enable the next generation of cell and gene therapies. A non-viral physical delivery technology, NanoStraws provide direct access to the cytosol of a cell and enable the delivery of Any Cargo into Any Cell in a gentle, non-perturbative manner. High cell viability, the ability to have multiple deliveries of different cargos into a cell, and no cargo size limitations are hallmarks of the platform. Cell transformation via NanoStraws will drastically reduce the complexity, cost and technical challenges involved in cell therapy manufacturing, allowing NAVAN to actively pursue the development of innovative therapies in a broad range of indications with its strategic collaborators and partners.

Nebula Biocides GmbH was founded in 2019 as a spin-off from the Leibniz Institute for Plasma Science and Technology (INP) by the scientists Dr. Jörn Winter, Dr. Ansgar Schmidt-Bleker and the director of INP Prof. Dr. Klaus-Dieter Weltmann. With the aim of providing comprehensive protection against infectious pathogens, the company develops application-oriented disinfection solutions that reliably kill not only bacteria and viruses but also persistent bacterial spores.

neotiv is a spin-off of the Otto von Guericke University in the German city of Magdeburg in close collaboration with the Magdeburg site of the German Centre for Neurodegenerative Diseases (DZNE). neotiv incorporates the latest scientific findings from the fields of neuroscience and dementia research into mobile software that can be used on smartphones and tablets. Our work focuses on the development of a digital assistant that can monitor and aid users' memories and provide support for patients with dementia. neotiv is also designed to improve the early detection of Alzheimer's dementia and to facilitate efficacy monitoring for new therapies as they become available in the future. Biologically and anatomically valid and user-oriented measurements of specific memory functions, which can be carried out on a regular basis, form the core of the development of neotiv. The measurements focus on regions of the brain that are affected in the early stages of Alzheimer's disease. The vision behind neotiv is to (i) help reducing risk factors for cognitive decline by making lifestyle change simple and cognitive health measurable and (ii) to enable the innovative early detection of cognitive difficulties and dementia risk.

Nia Health is a spin-off of the Charité Universitätsmedizin Berlin. The start-up develops a clinical diagnosis and therapy system for the continuous digital support of patients with chronic skin conditions. With its platform, Nia Health addresses an often highly underserved patient population and generates treatment-relevant real world evidence. With its innovative machine vision approach, Nia Health enables accurate documentation of disease and therapy progression and thus optimised treatment. The company works closely with German patient associations and leading clinicians and has already won reputable customers from
the insurance and pharmaceutical industries. Amongst others, the Berlin-based company has developed the award-winning apps in the fields of atopic dermatitis (Nia) and psoriasis (Sorea), which were the first digital medical products of their kind to be approved worldwide. The digital medical solutions from Nia Health provide daily support for thousands of patients and their families.

In order to successfully treat the infected patient, you have to recognize and diagnose most reliably the infecting microbe.
Noscendo changes the way infection causative microbes are identified. Through a paradigm shift we introduce by using proprietary algorithms and software harnessing next generation sequencing, we identify pathogens from cell free nucleic acids in patient samples and thereby aid intensive care clinicians in their daily task to find the right decisions, enabling a targeted and successful treatment in an actionable timeframe.