---
title: Rigontec (Exit)
date: 2014-11-04T13:20:21Z
modified: 2022-08-05T11:10:53Z
permalink: "https://www.htgf.de/en/portfolio/htgffamily/rigontec-2/"
type: portfolio
status: publish
excerpt: ""
wpid: 3271
language:
  - English
post_translations:
  - pll_544f987c64f2d
branchen22:
  - Oncology
timestamp: 2022-08-05T11:10:53Z
tags:
  - English
  - pll_544f987c64f2d
  - Oncology
---

## Beschreibungstext

Rigontec GmbH is a preclinical biotech company developing RNA-based immunotherapeutics for the treatment of cancer and viral diseases. Rigontec’s lead compound ImOl100 targets a novel receptor of the innate immune system, Retinoic acid Inducible Gene I (RIG-I).

## Lange Beschreibung

Rigontec GmbH, is a privately held biopharmaceutical company developing RNA-based immunotherapeutics for the treatment of cancer and viral diseases.

Rigontec focus on the development of synthetic ligands of a novel receptor of the innate immune system, Retinoic acid Inducible Gene I (RIG-I), which recognizes viral RNA. RNA motifs that activate RIG-I promote the destruction of diseased cells and the induction of a lasting immune memory thereby treating and preventing recurrence of disease.

Rigontec’s, a proprietary first-in-class product targeting RIG-I, is currently being evaluated for development in several cancer types including melanoma and prostate cancer. ImOl100 is a chemically synthesized mimic of the natural ligand of RIG-I with improved safety and drug like properties. In various preclinical models, ImOl100 has demonstrated substantial tumor regression and systemic anti-tumor activity including long-term protection against tumor rechallenge. Rigontec’s technology also allows the design of pipeline candidates with additional gene silencing and inhibitory activities. Rigontec is financed by top-tier VC investors and is seeking to realize the full potential of its technology by developing an internal pipeline into the clinic.

## Unternehmenswebsite

www.rigontec.de

## Adresse

Biomedizinisches Zentrum, Gebäude 344
Sigmund-Freud-Str. 25
53127 Bonn

## Kontakt

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