Key Facts

Invested since 2022
Based in Munich

About the company

smartbax is developing a new generation of antibiotics to address the increasing spread of multi-drug resistant bacteria. Their team of experts is advancing a complementary pipeline of small molecules against novel bacterial targets and with innovative modes of action to prevent resistance. Their lead program is a new inhibitor of lipopolysaccharide synthesis in Gram-negative bacteria. Moreover, the company specializes in the tailored activation of enzymatic pathways that trigger bacterial self-digestion, as this approach is particularly promising in the context of difficult-to-treat biofilms. Two activators are in development, targeting both Gram-positive bacteria and Gram-negative bacteria individually. Knowing that preventing a resistance crisis tomorrow means taking action today, smartbax was founded in 2021 as a spin-off of the Technical University Munich (TUM) with the aim of making innovative research applicable in creating novel antibiotics that add true value for patients worldwide.

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Dr. Angelika Vlachou Partner

Dr. Angelika VlachouPartner

smartbax in the news

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News

22 October 2025

smartbax announces a €4.7 M Pre-Series A round to advance novel antibiotic compound through preclinical stage

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News

23 May 2023

smartbax Announces Seed Financing of €1.2 Million to Develop Next-generation Antibiotics

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